ARROYO GARCÍA, CARMEN MARTINA, FELICIANO, F , KOLB, DL , KEELER, JR , MILLETTE, SR , STOTTS, RR
No
J. Biochem. Toxicol.
Article
Científica
01/06/1993
A1993LL37400007
The reaction of phosgene with nitrone spin traps was investigated using electron paramagnetic resonance (EPR)/spin trapping techniques. Evidence for the intermediacy of a carbamoyl monochloride intermediate was obtained. Isotopic substitution of C-13-phosgene was employed to verify the hyperfine coupling constant assignments. The implications of these observations on pulmonary damage caused by inhalation of phosgene are mentioned.
PHOSGENE; EPR; SPIN TRAPPING; CARBAMOYL MONOCHLORIDE RADICAL