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Effects of exercise-based interventions on health-related quality of life in adults after cancer: A systematic review and meta-analysis

Autores

Marmol-Perez A. , Gracia-Marco L. , Clavero-Jimeno A. , Amaro-Gahete F.J. , Ruiz J.R. , CARNEIRO BARRERA, ALMUDENA

Publicación externa

No

Medio

Ann Phys Rehabil Med

Alcance

Review

Naturaleza

Científica

Cuartil JCR

Cuartil SJR

Fecha de publicacion

01/01/2025

ISI

001482235300001

Scopus Id

2-s2.0-105002815479

Abstract

Background: Due to the lack of available knowledge in the current literature, this systematic review and meta-analysis was aimed to assess the effectiveness of exercise-based lifestyle interventions, including healthy diet and/or psychological well-being on mental, physical and global health-related quality of life (HRQoL) in adults after cancer treatment. Methods: MEDLINE (via PubMed) and Web of Science databases were searched for randomised controlled trials (RCTs) published until August 2024 evaluating exercise-based lifestyle interventions, including healthy diet and/or psychological well-being, which assessed mental, physical and global HRQoL. Results: Of 6193 screened studies, 32 RCTs met the criteria. The total sample comprised 5528 participants (3003 intervention and 2525 control). There was a small effect size in a pooled analysis that found exercise-based lifestyle interventions improve mental HRQoL (d 0.11, 95 % CI 0.05 to 0.18). These effects were greater in those studies that combined exercise with psychological well-being (d = 0.19, P = 0.004), and with moderate-to-high intensity aerobic exercise (moderate intensity; d = 0.11, P = 0.02, high intensity; d = 0.16, P = 0.02, aerobic exercise; d = 0.16, P = 0.26). Conclusions: Exercise-based lifestyle interventions do not enhance physical nor global HRQoL, yet those combined with psychological well-being seem to improve mental HRQoL in individuals after cancer treatment. PROSPERO registration number: CRD42022369169. © 2025 Elsevier Masson SAS

Palabras clave

Oncology; Physical activity; Psychology; Sport; Wellness

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