Título Secondary prevention of arterial disease in very elderly people:: Results from a prospective registry (FRENA)
Autores Lopez-Jimenez, Luciano , Camafort, Miguel , Tiberio, Gregorio , CARMONA CARMONA, JOSÉ ALBERTO, Guijarro, Carlos , Martinez-Penalver, Francisco , Monreal, Manuel , FRENA Investigators
Publicación externa Si
Medio Angiology
Alcance Article
Naturaleza Científica
Cuartil JCR 4
Cuartil SJR 2
Impacto JCR 1.122
Impacto SJR 0.44
Fecha de publicacion 01/08/2008
ISI 000259244900006
DOI 10.1177/0003319707309299
Abstract There is little information on the effectiveness of secondary prevention interventions in very elderly patients. In this article, the incidence of major cardiovascular events during a 12-month follow-up period in a series of consecutive patients with coronary, cerebrovascular, or peripheral artery disease is analyzed. As of October 2006, 1264 patients had been enrolled. Of these, 324 (26%) were >= 75 years of age. Their incidence rate of 22 events per 100 patient-years (95% CI, 17-28) was Over 2-fold the 7.9 (95% CI, 6.2- 10) found in those <75 years Of age. Among them, only chronic heart failure and diabetes were independently associated with an increased risk for major events, whereas the use of angiotensin II antagonists was associated with a lower risk. Patients >= 75 Nears of age had an over 2-fold higher incidence of major cardiovascular events. The use of angiotensin II antagonists was associated with a lower risk.
Palabras clave outcome; peripheral arterial disease; secondary prevention
Miembros de la Universidad Loyola