CASTEJÓN MARTÍNEZ, MARÍA LUISA, Montoya, T. , Alarcon-de-la-Lastra, C. , Gonzalez-Benjumea, A. , Vazquez-Roman, M. V. , Sanchez-Hidalgo, M.
No
Food Funct.
Article
Científica
1
1
5.396
1.145
01/07/2020
000551326500077
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease without an effective and safe treatment. Besides, macrophages are the major components of the innate immune system and play a critical role in the inflammation process in SLE. Secoiridoids from olive tree are phenolic compounds which have shown important pharmacological effects. Particularly, oleuropein (OL) has shown antioxidant, anti-inflammatory and immunomodulatory properties suggesting a potential application in a large number of inflammatory and reactive oxygen species (ROS)-mediated diseases. In addition, different studies have shown the importance of acyl derivatives of natural phenols due to their better hydrophilic/lipophilic balance.