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Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves

Authors

Lallemond, M. , Villeneuve, A. , MICALETTO BELDA, JUAN PABLO, Dubreuil, P.

External publication

No

Means

Vet. Rec.

Scope

Article

Nature

Científica

JCR Quartile

SJR Quartile

JCR Impact

1.168

SJR Impact

0.645

Publication date

11/11/2006

ISI

000242227700010

Abstract

Ninety, seven- to 10-day-old calves were allocated to three groups of 30 and treated daily for seven days with either 100 mu g/kg halofuginone hydrobromide or 2-5 mg/kg decoquinate orally or left untreated as controls. The levels of diarrhoea and dehydration were monitored daily for 28 days from the first day of treatment (day 0) and samples of faeces were collected on days 0, 7, 14, 21 and 28, to quantify the excretion of Cryptosporidium parvum oocysts. The calves were weighed on days 3 and 28. The treatments had no effect on the levels of diarrhoea or dehydration, the proportions of diarrhoeic calves or the proportions of calves shedding oocysts. However, unlike decoquinate, halofuginone significantly reduced the excretion of oocysts on day 7 (P < 0.0001), and decoquinate increased the average daily weight gain of the calves (P=0.049).

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