I am an Assistant Professor (Profesor Ayudante Doctor) at Universidad Loyola Andalucía working at the interface of developmental biology and genome engineering. My research focuses on optimizing CRISPR-Cas technologies for in vivo applications and studying early development and the maternal-to-zygotic transition in zebrafish. I obtained my PhD in Biotechnology from Universidad Pablo de Olavide (International Mention, Cum Laude), where I investigated virulence mechanisms in the phytopathogen Ustilago maydis . During my postdoctoral training, funded by the Margarita Salas mobility program, I further developed CRISPR-based tools for RNA regulation and functional genomics in Neuroscience Institute (CSIC-UMH) in Alicante and Andalusian Centre of Developmental Biology (CSIC-UPO) in Seville. I have authored eight Q1 publications, participating in six funded research projects, and actively combine research and dissemination (>25 contributions in national and international conferences and courses) with university teaching in Genetics and Biotechnology.
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CRISPR-RfxCas13d screening uncovers Bckdk as a post-translational regulator of maternal-to-zygotic transition in teleosts Hernandez-Huertas, Luis , MORENO SANCHEZ, ISMAEL, Crespo-Cuadrado, Jesus , Vargas-Baco, Ana , Da Silva Pescador, Gabriel , Zhang, Ying , Wen, Zhihui , Florens, Laurence , Santos-Pereira, Jose M. , Bazzini, Ariel A. , Moreno-Mateos, Miguel A. 01/12/2025 Article |
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Enhanced RNA-targeting CRISPR-Cas technology in zebrafish MORENO SANCHEZ, ISMAEL, Hernandez-Huertas, Luis , Nahon-Cano, Daniel , Martinez-Garcia, Pedro Manuel , Treichel, Anthony J. , Gomez-Marin, Carlos , Tomas-Gallardo, Laura , da Silva Pescador, Gabriel , Kushawah, Gopal , Egidy, Rhonda , Perera, Anoja , Diaz-Moscoso, Alejandro , Cano-Ruiz, Alejandra , Walker II, John A. , Munoz, Manuel J. , Holden, Kevin , Galceran, Joan , Nieto, M. angela , Bazzini, Ariel A. , Moreno-Mateos, Miguel A. 16/03/2025 Article |
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Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes Vicencio, Jeremy , Sanchez-Bolanos, Carlos , MORENO SANCHEZ, ISMAEL, Brena, David , Vejnar, Charles E. , Kukhtar, Dmytro , Ruiz-Lopez, Miguel , Cots-Ponjoan, Mariona , Rubio, Alejandro , Rodrigo Melero, Natalia , Crespo-Cuadrado, Jesus , Carolis, Carlo , Perez-Pulido, Antonio J. , Giraldez, Antonio J. , Kleinstiver, Benjamin P. , Ceron, Julian , Moreno-Mateos, Miguel A. 12/05/2022 Article |
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Optimized CRISPR-RfxCas13d system for RNA targeting in zebrafish embryos Hernandez-Huertas, Luis , Kushawah, Gopal , Diaz-Moscoso, Alejandro , Tomas-Gallardo, Laura , MORENO SANCHEZ, ISMAEL, Pescador, Gabriel da Silva , Bazzini, Ariel A. , Moreno-Mateos, Miguel A. 18/03/2022 Article |
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Ustilago maydis Secreted Endo-Xylanases Are Involved in Fungal Filamentation and Proliferation on and Inside Plants MORENO SANCHEZ, ISMAEL, Pejenaute-Ochoa, Maria Dolores , Navarrete, Blanca , Barrales, Ramon R. , Ibeas, Jose I. 01/12/2021 Article |
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N-glycosylation of the protein disulfide isomerase Pdi1 ensures full Ustilago maydis virulence Marin-Menguiano, Miriam , MORENO SANCHEZ, ISMAEL, Barrales, Ramon R. , Fernandez-Alvarez, Alfonso , Ignacio Ibeas, Jose 01/11/2019 Article |
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The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes Elias-Villalobos, Alberto , Fernandez-Alvarez, Alfonso , MORENO SANCHEZ, ISMAEL, Helmlinger, Dominique , Ibeas, Jose I. 01/08/2015 Article |
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Análisis de la expresión de marcadores tumorales en muestras de tumores humanos MORENO SANCHEZ, ISMAEL, Daga, Rafael R. , Horcajadas, José. A 03/04/2014 Article |
| Book chapters and books |
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Evaluación continua de TFG experimentales mediante la impartición de seminarios con audiencia pública 23/05/2025 Capítulo de un Libro |