Javier Lopez-Rios is an Assistant Professor at Universidad Loyola Andalucía and a tenured scientist (Investigador Científico, CSIC) at the Centro Andaluz de Biología del Desarrollo (CABD-CSIC), where he leads research on the gene regulatory networks that shape vertebrate morphogenesis. His work focuses on how changes in the genome can contribute to both human congenital malformations and the evolutionary diversification of limbs. He has published in leading journals including Nature , Developmental Cell , Nature Methods , PNAS and Cell Reports . He has secured more than €1.4 million in competitive funding and currently directs the CABD Animal Facility and the Functional Genomics Service, overseeing the implementation of advanced single-cell technologies. Alongside his research and teaching, he serves on the Board of the Spanish Society for Developmental Biology (SEBD) and is actively involved in public outreach and technology transfer.
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Functional architecture of cardiac TF regulatory landscapes in control of mammalian heart development. Roland, Virginia , Tüchler, Johannes , Esposito, Andrea , Conte, Mattia , Zoia, Matteo , Wisnumurti, Ekapaksi , Tissières, Virginie , Gamart, Julie , Rouco Garcia, Raquel , Marques, Ines J , Akshay, Akshay , Rapp, Vincent , Mannion, Brandon J , Akiyama, Jennifer A , Arora, Prateek , Walker, Harry , Hashemi Gheinani, Ali , Firulli, Beth A , Nusspaumer, Gretel , Firulli, Anthony B , Andrey, Guillaume , Visel, Axel , Mercader, Nadia , LÓPEZ-RÍOS MORENO, JAVIER, Nicodemi, Mario , Barozzi, Iros , Osterwalder, Marco 22/12/2025 Article |
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Uncovering hidden enhancers through unbiased in vivo testing Mannion, Brandon J. , Tran, Stella , Plajzer-Frick, Ingrid , Novak, Catherine S. , Afzal, Veena , Akiyama, Jennifer A. , Sospedra-Arrufat, Ismael , Barton, Sarah , Beckman, Erik , Garvin, Tyler H. , Godfrey, Patrick , Godoy, Janeth , Hunter, Riana D. , Kato, Momoe , Kosicki, Michael , Kronshage, Anne N. , Lee, Elizabeth A. , Meky, Eman M. , Pham, Quan T. , von Maydell, Kianna , Zhu, Yiwen , LÓPEZ-RÍOS MORENO, JAVIER, Dickel, Diane E. , Osterwalder, Marco , Visel, Axel , Pennacchio, Len A. 08/08/2025 Article |
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Range extender mediates long-distance enhancer activity Bower, Grace , Hollingsworth, Ethan W. , Jacinto, Sandra H. , Alcantara, Joshua A. , Clock, Benjamin , Cao, Kaitlyn , Liu, Mandy , Dziulko, Adam , Alcaina-Caro, Ana , Xu, Qianlan , Skowronska-Krawczyk, Dorota , LÓPEZ-RÍOS MORENO, JAVIER, Dickel, Diane E. , Bardet, Anais F. , Pennacchio, Len A. , Visel, Axel , Kvon, Evgeny Z. 17/07/2025 Article |
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Epigenomic signatures of cis-regulatory elements in the developing mouse and pig forelimb Sospedra-Arrufat, Ismael , Martinez-Garcia, Pedro Manuel , Gil-Galvez, Alejandro , Alcaina-Caro, Ana , Tena, Juan J. , Nusspaumer, Gretel , LÓPEZ-RÍOS MORENO, JAVIER 10/04/2025 Article |
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A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival. Abassah-Oppong, Samuel , Zoia, Matteo , Mannion, Brandon J , Rouco, Raquel , Tissières, Virginie , Spurrell, Cailyn H , Roland, Virginia , Darbellay, Fabrice , Itum, Anja , Gamart, Julie , Festa-Daroux, Tabitha A , Sullivan, Carly S , Kosicki, Michael , Rodríguez-Carballo, Eddie , Fukuda-Yuzawa, Yoko , Hunter, Riana D , Novak, Catherine S , Plajzer-Frick, Ingrid , Tran, Stella , Akiyama, Jennifer A , Dickel, Diane E , LÓPEZ-RÍOS MORENO, JAVIER, Barozzi, Iros , Andrey, Guillaume , Visel, Axel , Pennacchio, Len A , Cobb, John , Osterwalder, Marco 10/10/2024 Article |
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Increased enhancer-promoter interactions during developmental enhancer activation in mammals Chen, Zhuoxin , Snetkova, Valentina , Bower, Grace , Jacinto, Sandra , Clock, Benjamin , Dizehchi, Atrin , Barozzi, Iros , Mannion, Brandon J. , Alcaina-Caro, Ana , LÓPEZ-RÍOS MORENO, JAVIER, Dickel, Diane E. , Visel, Axel , Pennacchio, Len A. , Kvon, Evgeny Z. 01/04/2024 Article |
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The cellular landscape of the endochondral bone during the transition to extrauterine life Rueda, Alejandro Diaz , Salvador-Martinez, Irepan , Sospedra-Arrufat, Ismael , Alcaina-Caro, Ana , Fernandez-Minan, Ana , Burgos-Ruiz, Ana M. , Cases, Ildefonso , Mohedano, Alberto , Tena, Juan J. , Heyn, Holger , LÓPEZ-RÍOS MORENO, JAVIER, Nusspaumer, Gretel 01/02/2024 Article |
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Enhancer redundancy provides phenotypic robustness in mammalian development Osterwalder, Marco , Barozzi, Iros , Tissieres, Virginie , Fukuda-Yuzawa, Yoko , Mannion, Brandon J. , Afzal, Sarah Y. , Lee, Elizabeth A. , Zhu, Yiwen , Plajzer-Frick, Ingrid , Pickle, Catherine S. , Kato, Momoe , Garvin, Tyler H. , Pham, Quan T. , Harrington, Anne N. , Akiyama, Jennifer A. , Afzal, Veena , LÓPEZ-RÍOS MORENO, JAVIER, Dickel, Diane E. , Visel, Axel , Pennacchio, Len A. 08/02/2018 Article |
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The many lives of SHH in limb development and evolution LÓPEZ-RÍOS MORENO, JAVIER 01/01/2016 Review |