| Título | An Analytical-Experimental Approach to Quantifying the Effects of Static Magnetic Fields for Cell Culture Applications |
|---|---|
| Autores | FERRADA MARTINEZ, PABLO DANIEL, Rodriguez, Sebastian , Serrano, Genesis , Miranda-Ostojic, Carol , Maureira, Alejandro , Zapata, Manuel |
| Publicación externa | No |
| Medio | Appl. Sci.-Basel |
| Alcance | Article |
| Naturaleza | Científica |
| Cuartil JCR | 2 |
| Cuartil SJR | 2 |
| Impacto JCR | 2.679 |
| Impacto SJR | 0.435 |
| Fecha de publicacion | 01/01/2020 |
| ISI | 000522540400107 |
| DOI | 10.3390/app10020531 |
| Abstract | This work aimed to study the effects of static magnetic fields (SMFs) on cell cultures. A glass flask was filled with a liquid medium, which was surrounded by permanent magnets. Air was introduced through a tube to inject bubbles. Two magnet configurations, north and south, were used as perturbation. Scenedesmus obliquus and Nannochloropsis gaditana, growing in Medium 1 and 2, were subjected to the bubbly flow and SMFs. Differences between media were mainly due to conductivity (0.09 S/m for Medium 1 and 4.3 S/m for Medium 2). Joule dissipation (P) increased with the magnetic flux density (B-0), being 4 orders of magnitude higher in Medium 2 than in 1. Conversely, the time constant (tau(P)) depended on B-0, being nearly constant for Medium 1 and decreasing at 449 s/T for Medium 2. Dissipation occurred with the same tau(P) (235 s) in Medium 1 and 2 at B-0 = 0.5 T. In Species 1, the SMF effect was inhibitory. For Species 2, a higher enzymatic activity was observed. For superoxide dismutase, the relative difference was 78% with the north and 115% with the south configuration compared to the control values. For the catalase, differences of 29% with the north and 23% with the south configuration compared to control condition were obtained. |
| Palabras clave | fluid dynamics; static magnetic fields; Bessel functions; cell cultures |
| Miembros de la Universidad Loyola |