Título Design and rapid prototyping of DLC coated fractal surfaces for tissue engineering applications
Autores Díaz-Lantada A. , Mosquera A. , ENDRINO ARMENTEROS, JOSÉ LUIS, Lafont P.
Publicación externa Si
Alcance Conference Paper
Naturaleza Científica
Cuartil SJR 3
Impacto SJR 0.28800
Web https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952392098&doi=10.1088%2f1742-6596%2f252%2f1%2f012003&partnerID=40&md5=e8ed22648fd3482c8785070c0f9aa067
Fecha de publicacion 01/01/2010
Scopus Id 2-s2.0-79952392098
DOI 10.1088/1742-6596/252/1/012003
Abstract Several medical devices (both implantable and for in vitro diagnosis) benefit greatly from having microtextured surfaces that help to improve and promote phenomena such as osteointegracion and cell / tissue growth on the surface of a device. Normally, the use of abrasives or chemical attacks are employed for obtaining such surface microtextures, however, it is sometimes difficult to precisely control the final surface characteristics (porosity, roughness, among others) and consequently the related biological aspects. In this work, we propose an alternative process based on the use of fractal surface models for designing special surfaces, which helps controlling the desired contact properties (from the design stage) in multiple applications within biomedical engineering, especially regarding tissue engineering tasks. Manufacturing can be directly accomplished by means of rapid prototyping technologies. This method supposes a focus change from a conventional "top-down" to a more versatile "bottom-up" approach. Finally, in order to improve the possible biological response, the surfaces of the designed devices were coated with hydrogen-free amorphous carbon (a-C) thin films, known to be highly biocompatible materials. The films were deposited at room temperature using the vacuum filter cathodic arc technique. Our first prototypes have helped verify the viability of the approach and to validate the design, manufacturing and coating processes. © 2010 IOP Publishing Ltd.
Palabras clave Amorphous carbon; Amorphous films; Amorphous materials; Biocompatibility; Biological materials; Biomedical engineering; Biomedical equipment; Carbon films; Coated materials; Diagnosis; Films; Fractals
Miembros de la Universidad Loyola

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