Título Efficacy of different 8 h time-restricted eating schedules on visceral adipose tissue and cardiometabolic health: A study protocol
Autores Dote-Montero M. , Merchan-Ramirez E. , Oses M. , Echarte J. , Clavero-Jimeno A. , Alcantara J.M.A. , Camacho-Cardenosa A. , Cupeiro R. , Rodríguez-Miranda M.D.L.N. , López-Vázquez A. , Amaro-Gahete F.J. , González Cejudo M.T. , Martin-Olmedo J.J. , Molina-Fernandez M. , García Pérez P.V. , Contreras-Bolívar V. , Muñoz-Garach A. , Andreo-López M.C. , CARNEIRO BARRERA, ALMUDENA, Miranda-Ferrúa E. , Zugasti A. , Petrina E. , Álvarez de Eulate N. , Goñi E. , Ribelles M.J. , Brugos C.A. , Izquierdo C. , Fernández-Puggioni V. , Galbete A. , Villanueva A. , Medrano M. , Alfaro-Magallanes V.M. , Muñoz-Torres M. , Martín-Rodríguez J.L. , Idoate F. , Cabeza R. , Ruiz J.R. , Labayen I.
Publicación externa No
Medio Nutr Metab Cardiovasc Dis
Alcance Article
Naturaleza Científica
Cuartil JCR 2
Cuartil SJR 1
Fecha de publicacion 01/01/2024
ISI 001146635800001
DOI 10.1016/j.numecd.2023.09.014
Abstract Background and aims: To investigate the efficacy and feasibility of three different 8 h time-restricted eating (TRE) schedules (i.e., early, late, and self-selected) compared to each other and to a usual-care (UC) intervention on visceral adipose tissue (VAT) and cardiometabolic health in men and women. Methods and results: Anticipated 208 adults (50% women) aged 30–60 years, with overweight/obesity (25 = BMI<40 kg/m2) and with mild metabolic impairments will be recruited for this parallel-group, multicenter randomized controlled trial. Participants will be randomly allocated (1:1:1:1) to one of four groups for 12 weeks: UC, early TRE, late TRE or self-selected TRE. The UC group will maintain their habitual eating window and receive, as well as the TRE groups, healthy lifestyle education for weight management. The early TRE group will start eating not later than 10:00, and the late TRE group not before 13:00. The self-selected TRE group will select an 8 h eating window before the intervention and maintain it over the intervention. The primary outcome is changes in VAT, whereas secondary outcomes include body composition and cardiometabolic risk factors. Conclusion: This study will determine whether the timing of the eating window during TRE impacts its efficacy on VAT, body composition and cardiometabolic risk factors and provide insights about its feasibility. © 2023 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University
Palabras clave alanine aminotransferase; alkaline phosphatase; apolipoprotein A1; apolipoprotein B; bilirubin; calcium; creatinine; estradiol; ferritin; folic acid; gamma glutamyltransferase; glucose; hemoglobin A1c
Miembros de la Universidad Loyola

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