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The prevalence and risk of anxiety and depression in polycystic ovary syndrome: an overview of systematic reviews with meta-analysis

Autores

Infante-Cano, Marta , GARCÍA MUÑOZ, CRISTINA, MATÍAS SOTO, JAVIER, Pineda-Escobar, Saul , Villar-Alises, Olga , Martinez-Calderon, Javier

Publicación externa

No

Medio

Arch. Womens Ment. Health

Alcance

Review

Naturaleza

Científica

Cuartil JCR

Cuartil SJR

Fecha de publicacion

01/06/2025

ISI

001341166900001

Scopus Id

2-s2.0-85207364339

Abstract

PurposeTo summarize the pooled prevalence rates of anxiety and depression in women with polycystic ovary syndrome.MethodsAn overview of systematic reviews with meta-analysis was conducted. The CINAHL, Embase, PsycINFO, and PubMed databases were searched up to April 22, 2024. The methodological quality of systematic reviews was assessed using AMSTAR 2. The degree of overlap between reviews was analyzed by calculating the corrected covered area.ResultsTen systematic reviews were selected. Regarding anxiety disorders, the pooled prevalence of panic disorder, social phobia, and anxiety disorders without specifying the type of disorder were 4%, 5%, and 16.9%, respectively. This prevalence was higher in depressive disorders, reaching 34.8%. Anxiety symptoms were very prevalent in women with PCOS, although the prevalence varied depending on the self-reported questionnaire used: the Hamilton Anxiety Scale 69.4%, the Hospital Anxiety and Depression Scale 41.5%, and the Self-rating Anxiety Scale 32.4%. Additionally, the highest prevalence of depression symptoms was associated with the Beck Depression Inventory 46.0%, followed by the Self-rating Depression Scale 39.2%, and the Hospital Anxiety and Depression Scale, which ranged from 31% to 33.8%.ConclusionsMeta-analyses found mainly anxiety and depression symptoms and disorders are prevalent in women with PCOS. Meta-analyses also showed women with PCOS had a higher risk of having anxiety disorders, and depression symptoms than women without PCOS.Highlights center dot Anxiety symptoms were prevalent, although the prevalence varied depending on the self-reported questionnaire.center dot The highest prevalence of depression symptoms was associated with the Beck Depression Inventory (46.0%).center dot The pooled prevalence of anxiety disorders without specifying the type of disorder was 16.9%.Highlights center dot Anxiety symptoms were prevalent, although the prevalence varied depending on the self-reported questionnaire.center dot The highest prevalence of depression symptoms was associated with the Beck Depression Inventory (46.0%).center dot The pooled prevalence of anxiety disorders without specifying the type of disorder was 16.9%.Highlights center dot Anxiety symptoms were prevalent, although the prevalence varied depending on the self-reported questionnaire.center dot The highest prevalence of depression symptoms was associated with the Beck Depression Inventory (46.0%).center dot The pooled prevalence of anxiety disorders without specifying the type of disorder was 16.9%.

Palabras clave

Anxiety; Depression; Polycystic ovary syndrome; Prevalence; Overview; Systematic review

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