Ceballos, Manuel , Zampini, Giulia , Semyonov, Oleg , Funes-Hernando, Samuel , Vila-Fungueirin, Jose Manuel , Martinez-Gimenez, Sonia , Tatay, Sergio , Marti-Gastaldo, Carlos , Devic, Thomas , Pelaz, Beatriz , del Pino, Pablo
No
Cell Rep. Phys. Sci.
Article
Científica
7.3
18/12/2024
001393360100001
Porphyrinic metal-organic frameworks (MOFs) offer high surface areas and tunable catalytic and optoelectronic properties, making them versatile candidates for applications in phototherapy, drug delivery, photocatalysis, electronics, and energy storage. However, a key challenge for industrial integration is the rapid, cost-effective production of suitable sizes. This study introduces Zr(IV) alkoxides as metal precursors, achieving ultrafast (similar to minutes) and high-yield (>90%) synthesis of three well-known Zr-based porphyrinic MOF nanocrystals: MOF-525, PCN-224, and PCN-222, each with distinct topologies. By adjusting linker-to-metal and modulator-to-metal ratios, we attain precise control over single-phase formation. Demonstrating alkoxides' potential, we synthesized nanosized PCN-224 at room temperature within seconds using a continuous multifluidic method. This advancement greatly simplifies porphyrinic MOF production, enabling broader industrial and scientific applications.