Title Antibacterial properties of biomedical surfaces containing micrometric silver islands
Authors Pérez-Tanoira R. , Pérez-Jorge C. , ENDRINO ARMENTEROS, JOSÉ LUIS, Gómez-Barrena E. , Horwat D. , Pierson J.F. , Esteban J.
External publication Si
Means J. Phys. Conf. Ser.
Scope Conference Paper
Nature Científica
SJR Quartile 3
SJR Impact 0.28800
Web https://www.scopus.com/inward/record.uri?eid=2-s2.0-79952414780&doi=10.1088%2f1742-6596%2f252%2f1%2f012015&partnerID=40&md5=5fd70afb075717d33482fa07d32e1b8b
Publication date 01/01/2010
Scopus Id 2-s2.0-79952414780
DOI 10.1088/1742-6596/252/1/012015
Abstract A set of Cu-Mn-O and Ag-Cu-Mn-O films were sputter-deposited onto polished Ti-6Al-4V coupons and the microbiological adherence of Staphylococcus sp. was studied in these biomedical surfaces modified using advanced ternary and quaternary oxides that incorporated micrometric silver islands. The as-deposited ternary and quaternary compounds were amorphous. Upon air annealing the Ag-Cu-Mn-O films, silver-oxygen bonds in the compound destabilize, resulting in the segregation of metallic silver in the form of micrometric layered silver islands with high specific area dispersed at the surface of the remaining oxide. Silver is well known to have a natural biocidal character and its presence in the surface forming large micrometric escalonated islands is, in principle, predicted to enhance the antimicrobial properties of biomedical surfaces. Microbial adhesion tests were performed in triplicates using collection strains of Staphylococcus aureus and Staphylococcus epidermidis. Preliminary results indicate that both strains showed decreased adherence to modified materials, S. epidermidis showed higher adherence these materials than S. aureus, however, there was no statistically significant differences between Cu-Mn-O and Ag-Cu-Mn-O containing silver islands. © 2010 IOP Publishing Ltd.
Keywords Bacteria; Cell adhesion; Copper; Copper compounds; Manganese; Medical applications; Metallic compounds; Oxide films; Silver alloys; Surface segregation; Anti-microbial properties; Antibacterial proper
Universidad Loyola members

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