Title Biocompatible and Antibacterial SnO2 Nanowire Films Synthesized by E-Beam Evaporation Method
Authors Prasad, R. G. S. V. , Phani, A. R. , Rao, K. N. , Kumar, R. Rakesh , Prasad, S. , Prabhakara, G. , Sheeja, M. S. , Salins, C. P. , ENDRINO ARMENTEROS, JOSÉ LUIS, Raju, D. B.
External publication Si
Means J. Biomed. Nanotechnol.
Scope Article
Nature Científica
JCR Quartile 1
SJR Quartile 1
JCR Impact 3.92900
SJR Impact 0.92700
Web https://www.scopus.com/inward/record.uri?eid=2-s2.0-84918533506&doi=10.1166%2fjbn.2015.2025&partnerID=40&md5=5459cb2ea932cabe290ead4384ccc30e
Publication date 01/06/2015
ISI 000344969900002
Scopus Id 2-s2.0-84918533506
DOI 10.1166/jbn.2015.2025
Abstract In this work, the biocompatibility and antibacterial activities of novel SnO2 nanowire coatings prepared by electron-beam (E-Beam) evaporation process at low temperatures were studied. The nanowire coatings were characterized by scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), and X-ray diffraction (XRD) methods. The results of in vitro cytotoxicity and cell proliferation assays suggested that the SnO2 nanowire coatings were nontoxic and promoted the proliferation of C2C12 and L929 cells (> 90% viability). Cellular activities, cell adhesion, and lactate dehydrogenase activities were consistent with the superior biocompatibility of the nanowire materials. Notably, the nanowire coating showed potent antibacterial activity against six different bacterial strains. The antibacterial activity of the SnO2 material was attributed to the photocatalytic nature of SnO2. The antibacterial activity and biocompatibility of the newly developed SnO2 nanowire coatings may enable their use as coating materials for biomedical implants.
Keywords SnO2 NWs; Cytotoxicity; Cell Proliferation; Antibacterial Activity
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