| Title |
Effectiveness of interventions to prevent perinatal depression: An umbrella review of systematic reviews and meta-analysis |
| Authors |
MOTRICO MARTINEZ, EMMA, Bina R. , Kassianos A.P. , Le H.-N. , Mateus V. , Oztekin D. , Rodriguez- Muñoz M.F. , Moreno-Peral P. , Conejo-Cerón S. |
| External publication |
No |
| Means |
Gen Hosp Psychiatry |
| Scope |
Article |
| Nature |
Científica |
| JCR Quartile |
1 |
| SJR Quartile |
1 |
| Web |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150426338&doi=10.1016%2fj.genhosppsych.2023.03.007&partnerID=40&md5=e9a375f56ad779a18100227b697def0f |
| Publication date |
01/03/2023 |
| ISI |
000959774600001 |
| Scopus Id |
2-s2.0-85150426338 |
| DOI |
10.1016/j.genhosppsych.2023.03.007 |
| Abstract |
Background: To date, dozens of systematic reviews (SRs) and meta-analyses (MAs) summarize the effectiveness of preventive interventions for perinatal depression. However, the results are inconclusive, making an urgent need to step up to higher levels of evidence synthesis. Aims: To summarize and compare the evidence from the SR&MA examining the effectiveness of all types of interventions for preventing perinatal depression. Method: PubMed, PsycINFO, Cochrane Database of Systematic Reviews and OpenGrey were searched from inception to December 2022. We selected SR&MA of randomized controlled trials (RCTs) that compared all types of preventive interventions for perinatal depression with control groups whose outcome was the reduction of depressive symptoms and/or incidence of new cases of perinatal depression (PROSPERO: CRD42020173125). Results: A total of 19 SRs and MAs evaluated 152 unique RCTs that included 83,408 women from 26 countries and five continents. The median effect size for any intervention was SMD = 0.29 (95% CI: 0.20 to 0.38). Exercise/physical activity-based, psychological, and any type of intervention showed median effect sizes of 0.43, 0.28 and 0.36, respectively. The degree of overlap among RCTs was slight. According to AMSTAR-2, 79% of them were rated as low or critically low-quality. The strength of evidence, according to GRADE, was poorly reported and, in most cases, was low. Conclusions: Exercise/physical activity-based and psychological interventions have a small-to-medium effect on reducing perinatal depressive symptoms. There is insufficient evidence to conclude that dietary supplements and pharmacological interventions are effective in preventing perinatal depression. There is a need for high-quality SR&MA of RCTs, mainly focusing on universal preventive interventions. © 2023 |
| Keywords |
depression; meta-analysis; Perinatal; Prevention; Randomized control trial; systematic review |
| Universidad Loyola members |
|
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