Authors |
Bellón J.A. , Moreno-Peral P. , MOTRICO MARTINEZ, EMMA, Rodríguez-Morejón A. , Fernández A. , Serrano-Blanco A. , Zabaleta-del-Olmo E. , Conejo-Cerón S. |
Abstract |
Objective: To determine the effectiveness of psychological and/or educational interventions to prevent the onset of episodes of depression. Methods: Systematic review of systematic reviews and meta-analyses (SR/MA). We searched PubMed, PsycINFO, Cochrane Database of Systematic Reviews, OpenGrey, and PROSPERO from their inception until February 2014. Two reviewers independently evaluated the eligibility criteria of all SR/MA, abstracted data, and determined bias risk (AMSTAR). Results: Twelve SR/MA (156 non-repeated trials and 56,158 participants) were included. Of these, 142 (91%) were randomized-controlled, 13 (8.3%) controlled trials, and 1 (0.6%) had no control group. Five SR/MA focused on children and adolescents, four on specific populations (women after childbirth, of low socioeconomic status, or unfavorable circumstances; patients with severe traumatic physical injuries or stroke) and three addressed the general population. Nine (75%) SR/MA concluded that interventions to prevent depression were effective. Of the 156 trials, 137 (87.8%) reported some kind of effect size calculation. Effect sizes were small in 45 (32.8%), medium in 26 (19.1%), and large in 25 (18.2%) trials; 41 (29.9%) trials were not effective. Of the 141 trials for which follow-up periods were available, only 34 (24.1%) exceeded 12. months. Conclusion: Psychological and/or educational interventions to prevent onset of episodes of depression were effective, although most had small or medium effect sizes. © 2014 . |