| Title |
Impact of Multidisciplinary Prehabilitation Interventions on Postoperative Hospital Length of Stay and Functional Capacity in Patients Undergoing Resection of Colorectal Cancer: A Systematic Review and Meta-analysis |
| Authors |
Marmol-Perez A. , Corres P. , Fernández-Escabias M. , Carrilho-Candeias S. , Ruiz J.R. , Amaro-Gahete F.J. , CARNEIRO BARRERA, ALMUDENA |
| External publication |
No |
| Means |
DIS COLON RECTUM |
| Scope |
Article |
| Nature |
Científica |
| JCR Quartile |
1 |
| SJR Quartile |
2 |
| Web |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201064237&doi=10.1097%2fDCR.0000000000003268&partnerID=40&md5=9115f6b1a0d34360d3243a127bb76a31 |
| Publication date |
01/01/2024 |
| Scopus Id |
2-s2.0-85201064237 |
| DOI |
10.1097/DCR.0000000000003268 |
| Abstract |
BACKGROUND: Although surgery is commonly regarded as the primary curative treatment for colorectal cancer, it could potentially be associated with postoperative morbidity and mortality. OBJECTIVE: To determine the pooled effect of exercise and multidisciplinary prehabilitation interventions on postoperative hospital length of stay and functional capacity in patients undergoing resection of colorectal cancer. DATA SOURCES: A systematic search was conducted in MEDLINE (via PubMed) and Web of Science databases from inception to November 2022. STUDY SELECTION: The original systematic search retrieved 2005 studies. After the removal of duplicates and screening by title and abstract, 77 eligible full-text documents were evaluated for final inclusion in the meta-analysis. A total of 12 randomized controlled trials, 5 nonrandomized controlled trials, and 3 uncontrolled before-and-after studies were selected. MAIN OUTCOME MEASURES: Postoperative hospital length of stay (in days) and functional capacity (assessed with the peak of oxygen consumption [VO2 peak] and 6-minute walking test) were the outcome measures. RESULTS: The meta-analysis was conducted on 20 studies (3805 participants). Randomized controlled trials and nonrandomized controlled trials showed significant reductions in postoperative hospital length of stay (d = –0.10, nearly 2 days) and significant incremental improvements in VO2 peak (d = 0.27) and 6-minute walking test (d = 0.31). Regarding the before-and-after studies, the pooled effect of multidisciplinary prehabilitation interventions was positively significant for VO2 peak (d = 0.29) and 6-minute walking test (d = 0.29). There was no risk of publication bias (Egger test: p > 0.05), with a score of 0.71 (0–1) on average. LIMITATIONS: There was a high between-studies heterogeneity, and several outcomes did not have the required number of studies for a desirable statistical power. CONCLUSIONS: These findings suggest that multidisciplinary prehabilitation interventions might be effective at decreasing postoperative hospital length of stay (nearly 2 days) and improving functional capacity. © The American Society of Colon & Rectal Surgeons, Inc. |
| Keywords |
Colorectal Neoplasms; Humans; Length of Stay; Postoperative Complications; Preoperative Exercise; colorectal tumor; human; length of stay; meta analysis; postoperative complication; preoperative exercise; prevention and control; rehabilitation; surgery |
| Universidad Loyola members |
|
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