| Title | Influence of anodization conditions in hydrofluoric acid electrolyte on the optimization of TiO2 nanotube surfaces |
|---|---|
| Authors | SANDOVAL AMADOR, ANDERSON ANDRES, Nino, J. , Lopez-Rincon, J. F. , Carreno-Garcia, H. , Escobar-Rivero, P. , Duran, H. A. Estupinan , Pena-Ballesteros, D. Y. , ENDRINO ARMENTEROS, JOSÉ LUIS |
| External publication | No |
| Means | Appl. Phys. A-Mater. Sci. Process. |
| Scope | Article |
| Nature | Científica |
| JCR Quartile | 2 |
| SJR Quartile | 2 |
| Publication date | 08/07/2025 |
| ISI | 001524882200002 |
| DOI | 10.1007/s00339-025-08743-0 |
| Abstract | This study investigates the impact of anodization parameters (specifically, applied voltage, anodization time, and HF concentration) on the morphology, electrochemical response, and biocompatibility of TiO2 nanotubes formed on Ti6Al4V alloy. Different surface morphological features of amorphous-crystalline nanotubular structures were obtained by varying the anodization conditions. Surfaces with more ordered nanotubular structures showed higher corrosion resistance and greater cell adhesion, which are critical properties for biomedical applications. Among the morphological features obtained, larger nanotube diameters were correlated with higher hydrophilicity, which projects this type of coating towards the possibility of achieving higher protein adsorption and osteoblast adhesion capacity. Pearson correlation analysis revealed a strong positive effect between anodizing voltage and corrosion current density, with cell adhesion, observing a marked balance between these critical properties. Among the samples with nanotubular structures, those that were anodized at lower voltages and longer times showed higher corrosion resistance without significantly compromising biocompatibility. Furthermore, according to surface wettability analysis, larger nanotube diameters presented greater hydrophilicity, which is related to the possibility of improving extracellular matrix formation and cell interaction in the bone regeneration process. These findings highlight the importance of optimizing anodizing parameters to balance corrosion resistance and biocompatibility on TiO2 nanotube surfaces, contributing to the continued development of titanium-based implants with improved performance in biomedical applications. |
| Keywords | Nanotubes arrays; Anodization optimization; Hydrofluoric acid anodization; Titanium biocompatibility; Corrosion resistance optimization; Cell-material interaction; Biomedical surface functionalization; Titanium implant enhancement |
| Universidad Loyola members |