Title Multidisciplinary Prehabilitation and Postoperative Rehabilitation for Avoiding Complications in Patients Undergoing Resection of Colon Cancer: Rationale, Design, and Methodology of the ONCOFIT Study
Authors Amaro-Gahete F.J. , Jurado J. , Cisneros A. , Corres P. , Marmol-Perez A. , Osuna-Prieto F.J. , Fernández-Escabias M. , Salcedo E. , Hermán-Sánchez N. , Gahete M.D. , Aparicio V.A. , González-Callejas C. , Mirón Pozo B. , R. Ruiz J. , Nestares T. , CARNEIRO BARRERA, ALMUDENA
External publication No
Means Nutrients
Scope Review
Nature Científica
JCR Quartile 1
SJR Quartile 1
JCR Impact 5.9
SJR Impact 1.291
Web https://www.scopus.com/inward/record.uri?eid=2-s2.0-85141758679&doi=10.3390%2fnu14214647&partnerID=40&md5=35044752233e1d0cb5f3fa702c2d5c19
Publication date 03/11/2022
ISI 000881589800001
Scopus Id 2-s2.0-85141758679
DOI 10.3390/nu14214647
Abstract ONCOFIT is a randomized clinical trial with a two-arm parallel design aimed at determining the influence of a multidisciplinary Prehabilitation and Postoperative Program (PPP) on post-surgery complications in patients undergoing resection of colon cancer. This intervention will include supervised physical exercise, dietary behavior change, and psychological support comparing its influence to the standard care. Primary and secondary endpoints will be assessed at baseline, at preoperative conditions, at the end of the PPP intervention (after 12 weeks) and 1-year post-surgery, and will include: post-surgery complications (primary endpoint); prolonged hospital length of stay; readmissions and emergency department call within 1-year after surgery; functional capacity; patient reported outcome measures targeted; anthropometry and body composition; clinical/tumor parameters; physical activity levels and sedentariness; dietary habits; other unhealthy habits; sleep quality; and fecal microbiota diversity and composition. Considering the feasibility of the present intervention in a real-life scenario, ONCOFIT will contribute to the standardization of a cost-effective strategy for preventing and improving health-related consequences in patients undergoing resection of colon cancer with an important clinical and economic impact, not only in the scientific community, but also in clinical practice. © 2022 by the authors.
Keywords cardiovascular risk factors; exercise; nutrition; oncology; public health; tumor
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