Title Suicidality in primary care patients who present with sadness and anhedonia: a prospective European study
Authors Moreno-Kuestner, Berta, Jones, Rebeca, Svab, Igor, Maaroos, Heidi, Xavier, Miguel, Geerlings, Mirjam, Torres-Gonzalez, Francisco, Nazareth, Irwin, MOTRICO MARTINEZ , EMMA, Monton-Franco, Carmen, Jose Gil-de-Gomez, Maria, Sanchez-Celaya, Marta, Angel Diaz-Barreiros, Miguel, Vicens-Caldentey, Catalina, King, Michael, MOTRICO MARTINEZ , EMMA
External publication No
Means BMC Psychiatry
Scope Article
Nature Científica
JCR Quartile 2
SJR Quartile 1
JCR Impact 2.61300
SJR Impact 1.37500
Area International
Web https://www.scopus.com/inward/record.uri?eid=2-s2.0-84963577265&doi=10.1186%2fs12888-016-0775-z&partnerID=40&md5=27acda8a59c055a5f16af77dfa445574
Publication date 06/04/2016
ISI 000373426000005
Scopus Id 2-s2.0-84963577265
DOI 10.1186/s12888-016-0775-z
Abstract Background: Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia. Method: Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months. Results: 1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p < 0.0001), and suicide attempts (OR = 3.33; 95 % CI = 1.47-7.54; p = 0.0040) were significant predictors of persistent depression at 6 or 12 months. Conclusions: Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression.
Keywords Anhedonia; Depression; Primary care; Suicidality; Cohort; Risk
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