| Título |
Every Move Counts to Improve Bone Health at Clinical Sites in Young Pediatric Cancer Survivors: The iBoneFIT Project. |
| Autores |
Marmol-Perez, Andres , Migueles, Jairo H , Ubago-Guisado, Esther , GIL COSANO, JOSÉ JUAN, Rodriguez-Solana, Andrea , Redondo-Tébar, Andrés , Llorente-Cantarero, Francisco J , Labayen, Idoia , Ortega, Francisco B , Ruiz, Jonatan R , Gracia-Marco, Luis |
| Publicación externa |
No |
| Medio |
MEDICINE & SCIENCE IN SPORTS & EXERCISE |
| Alcance |
Article |
| Naturaleza |
Científica |
| Cuartil JCR |
1 |
| Cuartil SJR |
1 |
| Web |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85193309480&doi=10.1249%2fMSS.0000000000003397&partnerID=40&md5=6ca39445ea1005c2ced4226230c6370d |
| Fecha de publicacion |
01/01/2024 |
| ISI |
001226554900019 |
| Scopus Id |
2-s2.0-85193309480 |
| DOI |
10.1249/MSS.0000000000003397 |
| Abstract |
PURPOSE: We aimed to examine the associations of 24-hour movement behaviors (moderate-to-vigorous physical activity [MVPA], light physical activity [LPA], sedentary behavior [SB] and sleep) with age-, sex- and race-specific areal bone mineral density (aBMD) Z-score parameters at clinical sites in young pediatric cancer survivors. METHODS: This cross-sectional multicenter study was carried out within the iBoneFIT framework in which 116 young pediatric cancer survivors (12.1 ± 3.3 years old; 42% female) were recruited. We obtained anthropometric and body composition data (i.e., body mass, stature, body mass index and region-specific lean mass), time spent in movement behaviors over at least seven consecutive 24-hour periods (wGT3x-BT accelerometer, ActiGraph) and aBMD Z-score parameters (age-, sex- and race-specific total at the body, total hip, femoral neck and lumbar spine). Survivors were classified according to somatic maturity (pre or peri/post-pubertal depending on the estimated years from peak height velocity). The adjusted models\' coefficients were used to predict the effect of reallocating time proportionally across behaviors on the outcomes. RESULTS: In pre-pubertal young pediatric cancer survivors, reallocating time to MVPA from LPA, SB and sleep was significantly associated with higher aBMD at total body (B = 1.765, P = .005), total hip (B = 1.709, P = .003) and lumbar spine (B = 2.093, P = .001). In peri/post-pubertal survivors, reallocating time to LPA from MVPA, SB and sleep was significantly associated with higher aBMD at all sites (B = 2.090 to 2.609, P = .003 to .038). Reallocating time to SB from MVPA or LPA was significantly associated with lower aBMD at most sites in pre-pubertal and peri/post-pubertal survivors, respectively. Finally, reallocating time to sleep from MVPA, LPA and SB was significantly associated with lower aBMD at total body (B = -2.572, P = .036) and total hip (B = -3.371, P = .015). CONCLUSIONS: These findings suggest that every move counts and underline the benefits of increasing MVPA or LPA, when low MVPA levels are present, for bone regeneration following pediatric cancer treatment completion. |
| Palabras clave |
Accelerometry; Adolescent; Body Composition; Bone Density; Cancer Survivors; Child; Cross-Sectional Studies; Exercise; Female; Humans; Male; Sedentary Behavior; Sleep; accelerometry; adolescent; body composition; bone density; cancer survivor; child; clinical trial; cross-sectional study; exercise; female; human; male; multicenter study; physiology; sedentary lifestyle; sleep |
| Miembros de la Universidad Loyola |
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